GHRP-6
Also known as GHRP-6 Acetate, Growth Hormone Releasing Peptide-6
A growth hormone secretagogue peptide that activates ghrelin/GHS receptors and is studied for GH release, appetite signaling, and endocrine-axis pharmacology.
Overview
GHRP-6 is one of the older growth hormone releasing peptides. It activates the growth hormone secretagogue receptor, the same broad receptor family involved in ghrelin signaling.
The Science
GHRP-6 is useful historically because it shows how GH release can be stimulated outside the GHRH receptor pathway.
- GH release - stimulates pituitary growth hormone secretion.
- Appetite signaling - ghrelin-receptor activity can increase hunger.
- Endocrine selectivity - older GHRPs may have more off-target endocrine effects than newer agents such as ipamorelin.
Evidence Snapshot
GHRP-6 is a research secretagogue, not an approved anti-aging product. Interpretation should include GH pulses, IGF-1, glucose handling, appetite, and competitive-sport rules.
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