Humanin
Also known as Mitochondrial-derived peptide Humanin, HN
A mitochondrial-derived peptide studied for cellular stress resistance, apoptosis modulation, metabolic aging, neuroprotection, and mitochondrial communication.
Overview
Humanin is a mitochondrial-derived peptide first identified through neuroprotection research. It is part of a growing field studying peptides encoded by short open reading frames in mitochondrial or nuclear genomes.
The Science
Humanin is studied as a stress-response signal with effects in cell survival and metabolic models.
- Cell survival signaling - apoptosis and stress resistance.
- Mitochondrial communication - how mitochondria signal beyond energy production.
- Aging models - metabolic, vascular, and neurodegenerative research contexts.
Evidence Snapshot
Humanin is a research peptide with broad preclinical interest. Human translation remains much less established than the mechanistic literature.
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